Hyperglycemia is not properly managed. Marine-derived actinomycetes are rich sources of novel secondary metabolites which harbour unique structures and have diverse biological activities such as antimicrobial, antitumor and immunosuppressive activities. 
The obligate marine genera Salinispora and Marinispora have been characterized, and structurally unique and biologically active secondary metabolites have been isolated, such as salinosporamide A with excellent cytotoxicity from S. tropica CNB-392 and marinomycins A with strong antimicrobial and cytotoxic activities from Marinispora sp. CNQ-140. Marine-derived streptomycetes are also widely studied as novel antibiotic producers, where interesting compounds with antibacterial activities and anticancer activities were reported to be isolated. In our previous studies, a marine-derived actinobacterium Streptomyces xinghaiensis was identified to be a new species, which was proved to exhibit broad-spectrum antibacterial activities. However, so far no AbMole (R)-(-)-Modafinic acid sulfoxide antibiotic has been reported to be produced by microorganisms. The sulfoxide moiety presented in xinghaiamine A is unprecedented in metabolites from marine actinomycete. Sulfoxide compounds have broadspectrum of biological activities, including excellent antimicrobial, pesticidic and antitumor activities, and chemical synthesis of sulfoxide compounds also has aroused the interests of researchers. The isolation of xinghaiamine A seems to provide powerful potential to combat the emergence of multi-drugresistant microbial pathogens. In addition, compared with cisplatin, xinghaiamine A also displayed promising cytotoxic activities against a series of human cancer cell lines. Recently, the rapid development of resistance to multiple drugs in tumor chemotherapy has urged for the searching for novel drugs and the results above revealed that xinghaiamine A could be a potential clinically useful antitumor drug to combat with the increasing multi-drug resistant cancer cell lines, and the current study provided basis for further develop this novel compound for anticancer therapy. The oomycete Phytophthora capsici is a destructive fungus-like plant pathogen, which infects solanaceous and cucurbitaceous hosts including snap, lima, cucumber, eggplant, tomato, pepper, pumpkin, squash, melon, and zucchini. P. capsici has both a sexual and asexual life of cycle. Plants infected with P. capsici show various disease symptoms, such as foliar blights, fruit rots, stem and root rots. The preventive and frequent application of fungicides can limit disease expanding, but the increasing resistance of P. capsici to fungicides such as mefenoxam and pyrimorph, has been widely documented in some vegetable production regions. New fungicides aiming at different AbMole 4-(Benzyloxy)phenol targets need to be timely developed to overcome this resistance.