Tables S1, S2 and S3 demonstrate how they differed according to occupation type. Remission determined movement from a ��depressed�� to a ��recovered�� state, and relapse was the converse. The transition probabilities were derived from Vinblastine published findings from a national survey of the US population, in which diagnoses were made using the Primary Care Evaluation of Mental Disorders instrument. The PRIME-MD has been shown to have excellent agreement with clinical diagnoses made using the lengthier diagnostic interviews such as the CIDI. Treatment initiation probabilities determined movement from a ��not in treatment�� to an ��in treatment�� state. Age- and sexspecific mortality/survival rates determined movement to the ��deceased�� state. All depression states had an increased mortality rate due to risk of Alisol-A suicide, and an increased risk of early retirement. The deceased and retirement health states were absorbing states, which individuals could not leave once entered. Lost productive time, job turnover, depression-related service use and antidepressant medication costs were assigned to each health state. They were based on the probability of various cost-incurring events being experienced, the number of times that event occurred, and the unit cost assigned to that event. All costs were in 2007 Australian dollars, to reflect the reference year of the NSMHWB. Lost productive time costs involved multiplying the number of depression-specific absenteeism and presenteeism days, adjusted to a 3-month estimate, by the average daily wage. Daily wage, weekly wage and annual salary were calculated using the Australian Bureau of Statistics estimates of employee earnings and hours averaged across all occupations, and blue collar and white collar occupations separately, as defined by ANZSCO. Depression-related job turnover costs included the recruitment, hiring and training costs of replacing an employee who is terminated or voluntarily leaves. The job turnover probability estimate, although deemed the best available, was from a sample considered unrepresentative of the general population.